Ureaplasma decoding analysis 10. Questions

There are many infectious diseases that disrupt the functioning of the genitourinary system and other organs in women and men. One of the most common and insidious diseases is ureaplasmosis.

Another bacteriological culture is used to determine the sensitivity of microorganisms to antibiotics. Cultural way research is highly accurate, but the results will have to wait 4-8 days.

If the test results are ureaplasma 10 to 10, this indicates a large-scale lesion, which requires urgent treatment.

A quick and accurate analysis that helps identify ureaplasmosis in 98% of cases is PCR diagnostics.

For research, urine or vaginal discharge is taken.

Results are ready in 4 hours. The disadvantage of the method is the likelihood that the result will be false positive (if the person drank antibiotics before the study) and the lack of information about the activity of ureaplasmas.

The results of the analysis can be obtained in three days. Its disadvantage is that in the event of a failure, the body may not produce antibodies, so the infection will remain undetected.

Another way to detect antibodies is the serological method. For research take venous blood. Often this type of diagnosis is used to find out the causes of inflammatory processes, miscarriages and infertility.

Analysis results: ureaplasma 10 to 4 degrees

In the responses of the study to the presence of ureaplasma in the body, the amount of the pathogen is considered the leading indicator.

So, based on the numbers obtained, it is possible to determine whether the microorganism is dangerous to humans.

But it happens that ureaplasma is not detected, and a person is worried about unpleasant symptoms. In this case, you should be tested for other sexually transmitted infections.

Attention: found in 60% of patients, but many of them are only carriers of the infection.

When there are pathogenic microorganisms in the studied biomaterial, the result will be positive. But often the answer says ureaplasma 10 to the 4th degree. What it is? Such a result is considered the norm for bakposev. But sometimes an indicator of up to 105 CFU / mmol is allowed.

After all, much depends on the age, gender and general health of the person. If these figures are too high, then an additional analysis is carried out with the further appointment of antibacterial drugs.

Decryption

Only a physician should review test results..

After all, the names of microorganisms are written in Latin, which is incomprehensible to ordinary patients. Moreover, the presence of microorganisms such as ureaplasma is permissible, but in certain quantities.

On the form, in the first column, the name of the bacterium or virus is written, and then its concentration and degree of pathogenicity are indicated.

In conclusion, in the form of a separate table, the sensitivity of the pathogen to a particular type of antibiotic is indicated. Its level is indicated as follows:

• S - the microorganism is very susceptible;
• I – relative sensitivity;
• R - no reaction.

So, if the result of the analysis is ureaplasma 10 to the 4th degree, then its decoding says that such indicator is normal. Therefore, there is no need to treat with antibacterial and immunostimulating drugs.

Conclusion

It is worth remembering that with any weakening of the immune system or the addition of an infection, microorganisms can begin to multiply rapidly, which will lead to the development of ureaplasmosis.

To prevent this from happening, you need to eat right, avoid stress, do not forget about physical activity and give up unprotected sex.

In contact with

This degree implies treatment. However, some doctors believe that therapy in this case is inappropriate, and if patients do not have negative symptoms, then it can be abandoned.

Often, ureaplasma with high rates is found in young couples who have been trying to have a baby for a long period of time, and all attempts are in vain and unsuccessful. However, there is a danger for already pregnant women, so, for example, many are interested in,?

In the fairer sex, with such indicators, inflammation processes are observed that occur in the fallopian tubes, as a result of which the egg is blocked in the path to the uterus, and it cannot enter it.

A high concentration of ureaplasma in the body can lead to a number of concomitant diseases:

• Colpitis.
• Inflammatory processes in the fallopian tubes.
• Cervical erosion.
• Various processes of inflammation in the genitourinary system.
• Cystitis, endometritis.
• Violation of the functionality of the reproductive system.

Despite the fact that medical circles are still arguing whether ureaplasma should be treated or should be abandoned, numerous studies confirm that it can lead to spontaneous miscarriage in women or miscarriage.

Therefore, we can conclude that if ureaplasma is more than 10 * 4 degrees, then it is subject to mandatory therapy with the appointment of appropriate medications.

If ureaplasma is observed in a lower concentration, then treatment in this case is not recommended.

The disease does not always indicate its presence with negative symptoms, in a number of situations, the disease is asymptomatic, and it is possible to determine the pathology above the normal limit of 10 to 4 degrees only by passing biological material.

The condition of the vagina, pathogenic changes in the microflora can tell the doctor about the presence of pathology, and in this option, the doctor always offers to take additional tests to confirm or refute the suspected disease.

The collection of biological material for further study is taken from several places: the walls of the vagina, the cervical canal of the cervix, the urethra. The doctor distributes the resulting discharge over laboratory glass and sends it for analysis.

1. 2 days before the manipulation, it is necessary to refuse sexual intercourse.
2. Do not use suppositories, gels and topical ointments.
3. Avoid douching.
4. Hygienic intimate procedures are carried out in the evening, and washing should be excluded in the morning.

Reviews of doctors indicate that some drugs can lead to incorrect data, while you can get underestimated or overestimated results. In any case, this will lead to a worsening of the situation and the clinical picture.

Features of preparation for the method:

• You can not go to the toilet 3 hours before the manipulation.
• If a woman is taking antibiotics or antibacterial drugs, they should be discontinued a few days before the procedure.
• Two days before the procedure, give up suppositories and tablets that are inserted vaginally.
• On the day of the test, you can not perform intimate hygiene procedures.
• Exclusion of sexual intercourse a few days before the smear.

How to find ureaplasma in men?

To obtain biological material from a patient, the doctor scrapes the walls of the urethra. Reviews of men say that the procedure is not too painful, but uncomfortable.

The instrument is a special probe that is inserted into the urethra of a man, the approximate depth is 3 centimeters. Then the doctor uses several progressive movements to collect bacteria and particles of the mucous membrane.

When the probe is removed, the patient may feel slight discomfort in the urethra, burning and other unpleasant symptoms. They usually go away after a few days.

The procedure for passing tests requires certain preparatory measures not only for women, but also for men:

1. Two days before the manipulation, sexual intercourse is excluded.
2. Hygiene procedures are carried out the night before, it is impossible in the morning.
3. The analysis is recommended to be taken in such a way that the patient does not urinate for several hours.
4. Refuse to take antibiotics, antibacterial drugs a week before the analysis.

It is worth noting that the causes of the disease can also be factors - stress, severe nervous tension, hypothermia, and others. Even if the patient was found to have ureaplasma less than 10 to 4 degrees, he is at risk, and the disease can begin to develop at any time.

If one of the partners does not want to undergo treatment, believing that the test results showed nothing, then he is healthy, then the therapy of the second partner will be at risk, and in the vast majority of cases will be useless, a relapse of the disease is inevitable.

The main principles of therapy:

• A sparing dietary diet implies the exclusion of spicy, salty, smoked and pickled foods.
• In the vast majority of cases, antibiotics are not combined with the use of alcoholic beverages, so they must be abandoned during treatment.
• It is forbidden to have sex during therapy.

As a rule, antibiotics are always selected from the group of tetracyclines, macrolides, fluoroquinolones. The medicine must be taken orally according to the scheme recommended by the attending physician. The duration of treatment varies 7-10 days.

Upon completion of treatment, you do not need to immediately rush to take tests to find out about the effectiveness of therapy. Tests, as a rule, are given one or one and a half months after the completion of the medication.

Bacteriological culture (bacteriological culture) - this is a microbiological laboratory study of human biological material by inoculation on certain nutrient media at a certain temperature regime in order to detect the presence of any number of pathogenic and opportunistic microorganisms in it and further solve the problems of specific treatment.

When certain microorganisms are isolated, a second important analysis is carried out - antibiogram – determination of the sensitivity of detected pathogens to antibacterial drugs and bacteriophages.

The advantages of bacteriological culture are:

High specificity of the method (that is, no cross-false reactions are observed).
The ability to explore absolutely any human biological fluid.
The therapeutic goal is to determine the sensitivity of the identified microbe to a particular therapeutic agent (antibiogram), which allows for a sufficiently high accuracy to carry out medical appointments.

Disadvantages of bacteriological culture:

The duration of the result.
High demands on material intake.
Certain requirements for the qualification of personnel of bacteriological laboratories.

Indications for bacteriological examination

The use of the microbiological research method is quite widespread in medical practice, in particular, in infectious diseases, gynecology, urology, surgery, otolaryngology, oncology, and others. Any inflammatory disease of the organs and systems of the human body, suspicion of a septic process are an unconditional indication for the need for bakposev.

material for bakposev

The following biological media of the human body are taken for research: nasopharyngeal mucus, pharyngeal mucus, bronchial tree secretion (sputum), feces (feces), mucus of the urethra, cervical canal, prostate secretion, urine, blood, cerebrospinal fluid, breast milk, bile, contents cysts, inflammatory foci, wound discharge.

What microorganisms can be detected by bakposev

In the mucus of the nose and throat, hemolytic streptococci (Streptococcuc pyogenes, Streptococcuc agalactiae), pneumococci (Streptococcuc pneumoniae), Staphylococcus aureus (Staphylococcus auereus), corynebacterium diphtheria (Corynebacterium diphtheriae), hemophilic bacillus (Haemophilus influenzae type b), meningococcus (Neiitococcus) can be found. ), Listeria (Listeria).

In the feces, they try to identify the intestinal group of bacteria - Salmonella and Shigella (Salmonella spp., Shigella spp.), Yersinia (Iersiniae spp.), Typhoid-paratyphoid group of bacteria (Salmonella typhi, Salmonella paratyphi A, Salmonella paratyphi B), opportunistic pathogens of intestinal infections, anaerobic microbes, pathogens of food toxic infections, as well as examine feces for intestinal dysbacteriosis.

Pseudomonas or Pseudomonas aeruginosa (Pseudomonas aeruginosa) can be detected in the contents of wounds, biopuncture, purulent discharge.

The mucus of the urogenital tract is examined for the presence of sexually transmitted infections in it - gonococcus, Trichomonas, fungi (Neisseria gonorrhoeae, Trichomonas vaginalis, fungi of the genus Candida), ureaplasma (Ureaplasma urealyticum), mycoplasma (Mycoplasma hominis), listeria (Listeria), you can also examine the smear for bacterial flora.

Blood can be sown (examined) for sterility.

Materials such as breast milk, urine, prostate secretions, scrapings, swabs, wound contents, joint fluid, bile are examined for general contamination (bacterial flora).

What is bacteriological culture?

Material for research in a bacteriological laboratory is placed (inoculated) on special nutrient media. Depending on the desired search for a particular pathogen or group of pathogens, sowing is carried out on different media. For example, it can be a selective or selective nutrient medium (for the growth of one pathogen, the growth of other microbes is inhibited), an example of which can be clotted horse serum to detect diphtheria pathogens or a medium with selenite or bile salts to detect intestinal pathogens.

Another example would be differential diagnostic media (Hiss media), which are used to decipher bacterial cultures. If necessary, liquid nutrient media are transferred to solid media in order to better identify the colonies.

Then the nutrient media are placed in a thermostat (a special device), in which favorable conditions (temperature, humidity, etc.) are created for the growth and reproduction of pathogens, and they stay in the thermostat for a certain time.

Next, a control examination of the grown colonies of microorganisms is carried out, which is called the "culture of microorganisms". If necessary, microscopy of the colony material is carried out with preliminary staining with special dyes.

What is assessed during the control examination? This is the shape, color, density of colonies, after additional research - the ability to decompose some inorganic and organic compounds.

The next step is to count the pathogens. In microbiological research, such a concept is taken into account as colony forming unit (CFU) - one microbial cell capable of forming a colony, or a visible colony of microbes. By CFU it is possible to determine the concentration or number of microorganisms in the test sample. CFU counting is carried out by different methods: counting colonies under a microscope, serial dilution method, sector method.

Rules for the collection of biological material for bacteriological seeding

The quality of the conducted bacteriological seeding largely depends on the correctness of the sampling of material for research. You need to remember a simple rule: sterile dishes and sterile instruments! Failure to comply with these requirements will lead to contamination (external contamination of the material by representatives of the skin and mucous membranes, the environment, which do not have clinical significance), which will automatically make the study meaningless. To take the material, sterile dishes are used, which are given out in the bacteriological laboratory itself to the hands of the patient during an outpatient examination, for the collection of feces and urine. From various foci of inflammation, the sampling is carried out only with sterile instruments (spatulas, loops, spoons) by a specially trained medical worker (in a polyclinic, this is usually a nurse in an infectious or examination room).

Blood and urine are collected in dry test tubes, the rest of the materials are collected in a container with a transport nutrient medium.

Another rule: sampling before starting antibiotic therapy! Against the background of taking antibiotics, the result will be significantly distorted. If you took such drugs, then stop taking them 10 days before the study and inform the doctor about the fact of taking any antibacterial drugs.

Rapid delivery to the laboratory must be ensured! Microorganisms can die when dried, changing acidity. For instance, feces must be delivered warm.

When collecting urine: after morning hygiene procedures, an average portion of morning urine in the amount of 10-15 ml is taken into a sterile dish. Deliver to the laboratory within 2 hours.

When taking a swab from the pharynx and nose: you can’t brush your teeth in the morning, rinse your mouth and nose with disinfectant solutions, drink and eat.

Stool collection should be done in the morning with a sterile spatula in a sterile dish in a volume of 15-30 g. It is unacceptable to get into the urine sample. Delivery within 5 hours. Freezing or overnight storage is not allowed. Collect feces without the use of enemas and laxatives.

Blood for bacterial culture taken before the start of antibiotic therapy against the background of a rise in temperature in a sterile test tube in an amount of at least 5 ml (children), at least 15 ml (adults).

Sputum collected in the morning on an empty stomach in a sterile container during an attack of coughing with mucus. Before the fence, brush your teeth and rinse your mouth with boiled water. Deliver to the laboratory within 1 hour.

Breast milk collected after a hygiene procedure. The peripapillary region is treated with a swab moistened with 70% ethyl alcohol. The first 15 ml of expressed milk is not used. Then 5 ml is decanted into a sterile container. Deliver within 2 hours.

Detachable genitals: in women, sampling is carried out no earlier than 14 days after menstruation, no earlier than 1 month after antibiotics are discontinued, it is advisable not to urinate for 2 hours; in men - it is not recommended to urinate for 5-6 hours before sampling.

Terms of readiness of bacteriological seeding

When examining mucus from the nasopharynx, the result will be ready in 5-7 days, the study of feces will take about 4-7 days. When examining a scraping of the urogenital tract, the duration of the study will take 7 days. Sowing on the general flora lasts 4-7 days. Most of all, blood is prepared for sterility in duration - 10 days. However, the earliest preliminary result can be given after 3 days.

The result of bacteriological research

The result of bakposev is both a qualitative assessment (the very fact of the presence of a pathogen in the test sample) and a quantitative assessment (the concentration of the pathogen in the material).

Deciphering the quantitative result is carried out in the simplest way. There are 4 degrees of growth (contamination) of microorganisms in the test material. For the 1st degree of growth, poor growth is characteristic only on a liquid medium, on a solid one - there is no growth; for grade 2 - growth on a dense medium up to 10 colonies of the same species; for grade 3 - from 10 to 100 colonies; for grade 4 - more than 100 colonies.

This is important for opportunistic flora, in the detection of which grades 1 and 2 are not considered the cause of the disease, this simply indicates the contamination of the material for research, grades 3-4 indicate the etiology (cause) of the disease. If the pathogenic flora is isolated, then all isolated colonies are taken into account without exception, that is, all 4 degrees.

The result of counting colonies in CFU / ml is decoded as follows: 103 / ml means the detection of 1 colony; 104/ml - from 1 to 5 colonies; 105/ml - growth of 5-15 colonies; 106 / ml - more than 15.
The quantitative result is important not only for determining the degree of contamination, but also for monitoring the correctness of the treatment.

Determining the sensitivity of an isolated microorganism to a particular antibacterial drug is an important component of bacteriological research. A set of drugs to which the pathogen is sensitive or resistant, and is antibiogram .

The sensitivity of the pathogen is the susceptibility to the drug, that is, the antibiotic will affect the growth and reproduction of the microbe. Resistance - the resistance of the pathogen to a particular drug, that is, the antibacterial drug will not work.

The antibioticogram is issued in certain units of measurement - the minimum inhibitory concentration (MIC).

Infectious disease specialist Bykova N.I.

bacterium enterococcus faecalis, found in a smear, it is also fecal or intestinal enterococcus, it is a microorganism that usually lives in the human intestine and is opportunistic. That is, it can cause a disease, but only under certain conditions - if it gets into a favorable environment for it (in the mouth, vagina, urinary system) with reduced immunity (typical for pregnancy). It provokes cystitis, aerobic vaginitis, pyelonephritis and other diseases.

The gynecologist diagnoses this pathogen according to the results of bakposev on the flora. This is an analysis that is sometimes taken from expectant mothers in a planned manner without any complaints, as well as in case of a poor overall smear, if too many leukocytes are found.

Sometimes a swab for flora or purity from the vagina is taken simultaneously with a bacterial culture. This is if a woman already has symptoms of a gynecological disease, infection, for example, unusual discharge, itching. Thus, it will be possible to prescribe the correct treatment in a shorter time, because sowing is performed more than one day. It is necessary to wait until microorganisms multiply in the discharge from the vagina and cervical canal, taken for analysis.

Enterococcus faecalis symptoms in women

Fecal enterococcus is found in smears in 25% of women, and more often this is the norm. It does not always give any symptoms. If the amount of the microorganism is not large, perhaps it even got into the smear from the rectum due to its incorrect taking from a healthy woman, the bacterium does not give any signs.

If aerobic vaginitis develops - inflammation of the vagina caused by a sharp increase in aerobic microflora (including Enterococcus faecalis), that is, microorganisms that need oxygen for development, then the severity of the symptoms of the disease will depend on its degree. You can judge in more detail about the stages of development of aerobic vaginitis from the table.

For clarity in numbers:

• 10 to 2 degrees or 10 to 3 degrees - moderate growth, probably enterococcus got into the vagina from the rectum by accident;
• 10 * 4 cfu / ml, 10 ^ 5, 10 ^ 6, 10 in the 7th degree - abundant growth.

If there is inflammation, then there will be its following manifestations.

1. Pain during intercourse, the so-called dyspareunia.
2. Abundant yellow discharge without an unpleasant odor (unlike bacterial vaginosis caused by anaerobic microorganisms, when there is a smell of rotten fish).
3. Swelling and redness of the vestibule and walls of the vagina.
4. Itching and burning in the vagina. Sometimes women complain that they pinch the labia.

Listed body signals become especially bright after menstruation.

Periodically, the symptoms become less pronounced, the woman feels better, but then an exacerbation follows again.

Causes of intestinal enterococcus in the vagina and ways of infection

From the intestine, microorganisms enter the vagina during anal-vaginal contacts, normal sexual intercourse; due to the proximity of the anus and the entrance to the vagina, improper washing and wearing thongs, poor personal hygiene, etc.

Especially often aerobic vaginitis occurs in girls and in women during menopause. The problem is low estrogen, little or no lactobacilli. To improve the microflora of the vagina, to populate it with beneficial microorganisms for women with menopause, hormone replacement therapy, including the use of topical preparations - Ovestin, will help. By the way, another gynecological pathology is associated with a low level of estrogen -.

During sexual intercourse, it can be transmitted from one partner to another, like any other opportunistic pathogen, but in small quantities.

Treatment of fecal enterococcus in women

If there are no symptoms of the disease, no treatment is required. If there is, then antibiotics are prescribed orally and a local antibacterial or antiseptic drug is prescribed.

There is an opinion that it is necessary to be treated if fecal enterococcus is detected when taking a smear from the cervical canal. Allegedly, it can be observed only if it is located exclusively in the vagina. But the microflora of the vagina and the cervical canal are almost identical. And pathogenic microorganisms simply do not get into the uterus. The mucous plug will interfere (it is formed not only in pregnant women!), menstruation (during it the endometrium is rejected with all pathogenic bacteria), constant physiological renewal and leucorrhoea - vaginal discharge also “cleans” the mucous membrane.

Of the antibiotics, preference is usually given to the following:

• "Gentamicin;
• "Sizomycin";
• "Amicin";
• "Tobramycin";
• "Netilmicin";
• "Levofloxacin";
• "Linezolid";
• "Amoxiclav";
• "Amoxicillin";
• "Levofloxacin";
• "Cefotaxime";
• "Rifaksimin";
• "Nifuratel";
• "Ceftriaxone";
• "Ciprofloxacin".

Pefloxacin, lomefloxacin, ofloxacin, norfloxacin are weakly active. The result of bakposev helps to determine the effective medicine more accurately. As a result of this analysis, you will find to which antibiotic the bacterium is resistant (immune) and sensitive.

Of the local drugs to fight enterococcus faecalis help:

• Terzhinan;
• Polygynax;
• Hexicon.

Treatment regimen No. 1	"Gentamicin" 2 times a day for 5 days + candles "Terzhinan" 1 before bedtime - 10 days. After that, it is possible to use drugs to normalize the intestinal and vaginal microflora. "Bifidumbacterin" inside and "Acilact" vaginally. But this is optional.
Treatment regimen No. 2	1 candle "Vaginorm C". The next day, antibiotics "Ciprofloxacin" at a dosage of 500 mg 2 times a day for a week. In parallel with this, candles "Terzhinan" 1 piece for 10 days. After the end of the course of antibiotics - another 5 days of "Vaginorm C" and then to restore the microflora of the vagina "Ecofemin" for 10 days.
Treatment regimen No. 3	"Ampicillin" at a dosage of 0.25, 2 tablets 4 times a day for one week. At night, 1 suppository "Hexicon" vaginally.
Treatment regimen No. 4	"Ciprinol" 500 mg 2 times a day. On the 3rd and 10th day of antibiotic treatment - Mikomax 150 mg. From the second day of treatment with antibiotics inside, vaginally combined antibiotic "Polygynax" for 12 days. After that, restore the vaginal microflora with Vaginorm-S suppositories (6 days).

Some doctors resort to an alternative treatment - boosting immunity so that the body can fight the intestinal microorganism on its own. Or prescribe a bacteriophage for the intestines. Proponents of evidence-based medicine are skeptical about such prescriptions. "Rifaksimin", "Viferon" and similar drugs do not have proven efficacy and safety.

If there are manifestations of a fungal infection (thrush) - appoint "Macmirror".

Pregnant women cannot do without antibiotics, since for them the consequences of this inflammatory process can be especially severe.

What is dangerous aerobic vaginitis, the consequences of the disease

It is possible to develop severe endocolpitis - an inflammatory-dystrophic lesion of the walls of the vagina and cervix. This often provokes the following complications during pregnancy:

• premature rupture of the amniotic sac with discharge of amniotic fluid;
• chorioamnionitis;
• premature birth;
• intrauterine growth retardation;
• having a low birth weight baby.

Aerobic vaginitis is exacerbated by pelvic inflammatory disease:

• endometritis;
• salpingitis;
• oophoritis;
• tubo-ovarian abscess;
• pelvic peritonitis.

Symptoms of diseases of the female reproductive organs:

• severe pain during menstruation and in other phases of the cycle; pain radiates to the lower back, sacrum, perineum;
• sensation of heat and fullness in the perineum;
• pain during intercourse and decreased libido;
• infertility;
• mucous, gray leucorrhoea;
• increase in body temperature;
• pain when urinating.

Complications of diseases of the reproductive organs:

• scarring, adhesions in the fallopian tubes;
• ectopic pregnancy;
• regular pelvic pain;
• tubo-ovarian abscess;
• pelvioperitonitis.

Concomitant enterococcus faecalis opportunistic flora and terms

You can read these scientific definitions in the results of the analyzes. You should not be afraid of these microorganisms. All of them are opportunistic pathogens. They don't always cause disease. They are aerobic, that is, they are capable of provoking aerobic vaginitis.

Since ureaplasmosis mainly affects the mucous organs of the genitourinary system, a smear with microflora culture is used to determine the presence of parvum and urealiticum bacteria, as well as to determine their titer. For the first time, they started talking about bacteria in the middle of the last century. Then it was considered a purely female disease, and closer to the 60s, the bacterium was found in men.

Then, in the course of studies of various pathogenic microflora of the urethra and vagina, it was found that more than half of people of reproductive age have parvum or urealiticum bacteria, which means that a diagnostic method is needed that would allow determining the titer of bacteria.

New studies began, the purpose of which was to determine the degree of risk of developing the disease at different titers. It was found that ureaplasma 4 CFU / tamp or more to the 10th degree is the boundary when a conditionally pathogenic bacterium turns into a pathogenic one and the development of ureaplasmosis begins. In order for the indicator of ureaplasma parvum 10: 4 CFU / tamp in the results of the culture tests to be true, and not be less than the real titer, before taking a smear, you should stop taking drugs that can affect the final result.

Very often, grade 4 ureaplasma is detected during a survey of young couples who have unsuccessfully tried to have a baby for a long time, which is not surprising, because with such an amount this bacterium can have a detrimental effect on spermatozoa, destroying and slowing them down, which leads to male infertility. In women, with indicators of 10 in the fourth degree, inflammatory processes occur in the fallopian tubes, due to which the egg may not enter the uterus.

To determine ureaplasma urealyticum 10:4 CFU / tamp, a swab is taken from the vagina in women and the urethra in men, then the bacterium is placed in a nutrient medium (inoculation), and only then the titer is calculated. sensitivity to different groups of antibiotics, and treatment is prescribed. With indicators of ureaplasma less than 10: 4 degree, treatment can be prescribed only with obvious signs of an inflammatory process and the absence of other microflora with a titer higher than that of this bacterium.

An exception is the situation in which ureaplasma with a titer of 10:4 CFU / tamp is detected in the early stages of pregnancy, in which case harmful therapy is postponed to a later date (weeks 20-22) in order to avoid pathologies of fetal development.